COMPARISON OF EFFICACY OF LIGHTENING PEEL VERSUS IPL FOR TREATMENT OF EPIDERMAL MELASMA

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Published: 2025-07-18
Keywords:
Dermal melasma, treatment, Intense pulsed light, Chemical peeling, Glycolic acid (GA)

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Dr Mahnoor Farooq
Dr. Ali Amar
Dr Muhammad Asfand Yar Khan
Dr Shams Ul Haq
Dr Aleena Nasir Khan
Dr Anees ur Rahman

Abstract

Background: Epidermal melasma remains a therapeutic challenge, with limited real-world data comparing Lightening Peel and IPL.


Objective: To evaluate the efficacy and safety of Lightening Peel (glycolic acid 30%) versus Intense Pulsed Light (IPL) in cases of epidermal melasma.


Methods: Prospective observational cohort study conducted at the Dermatology Department of CMH Abbottabad, involving 80 patients with epidermal melasma (diagnosed using Wood's lamp). Patients were treated either with Lightening Peel (n=40) or Intense Pulsed Light (IPL) therapy (n=40). Outcomes measured included reduction in MASI score, adverse events, and patient satisfaction at 6 months.


Results: Lightening Peel had greater reduction of MASI score (42% vs. 28%, p=0.003), fewer PIH occurrences (5% vs. 18%, p=0.02), and greater rates of satisfaction (78% vs. 55%, p=0.01) compared to IPL.


Conclusion: In clinical practice, Lightening Peel might be more effective and better tolerated in epidermal melasma than IPL.

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Issue

Vol. 3 No. 7 (2025): The Research of Medical Science Review

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Articles
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

How to Cite

COMPARISON OF EFFICACY OF LIGHTENING PEEL VERSUS IPL FOR TREATMENT OF EPIDERMAL MELASMA. (2025). The Research of Medical Science Review, 3(7), 1875-1880. https://www.medscireview.net/index.php/Journal/article/view/1802